Atelier Rorona: The Alchemist of Arland

When you're not gathering items in dungeons, you're performing alchemy in the comfort of your workshop. Reach Lv. 50 in alchemy, and the trophy will unlock. You will most likely unlock this naturally.

After the initial first Year, money should not pose as a problem. As a general rule, the higher Lv. an item requires to make (located in the top right corner of each item during synthesis), the more Exp you'll earn. In addition, when synthesizing, take note of the amount of days that's required to make the item. For example, it takes 1 day to make a Supplement, but it also only takes 1 day to make 5 Supplements. Learn to create as many items as possible in the lowest amount of time to earn the most experience.

To make synthesizing more efficient in terms of time wise, have Hom do all the gathering for you if you have no reason to head to a dungeon. Not only does this level him/her up as well, it'll save you time.