Bionic Commando

The Nerevarine - I contribute my success to you.

However, here is my take/adjustments on Commando.

Snipers actually take 2 shots, but the shots can be spaced around 1 1/2 seconds apart. If your swinging, speed it up and you'll get too cover in time.

When there's multiple Biomechs, never stay still for too long. They WILL get you, and it will HURT. Kiting/Throwing takes too much time to really be a viable attack, but the punch up and kick combo keeps you in cover (Technically) and hurts them quite a bit. Preferable attack there.

As said in the previous solution, skipping sections IS possible. However, if you can see one of those odd blue barriers in the distance, do NOT get close. There's likely a 'heavy' type enemy waiting to drop in so you can open the door. If your in an area with snipers and such, make sure to kill them first. Otherwise, you're not likely too make it.

Try and go for alot of the easier challenges, as the rewards (such as a health upgrade) are really helpful. Any ammo increases and such are great as well. However, I advise against collectibles. On Commando, it's a waste of time.

I completed Commando in around 7 hours gametime, taking breaks here and there for food and such. It's not too hard, just follow the tips from both of these solutions.

The Nerevarine - I contribute my success too you :)

Both The Nerevarine's and StarSnapShot's guides are very useful!

If I may add a few helpful details.

Grunts: Take advantage of the walls and covers. Most of the times, the grunts will not even bother to find a different shooting angle. They also tend to group up close to your position. A perfect example is just before fighting the 2 biomechs in front of the FSA Building in Ascension City. There will be a lot of Grunts parachuting to your location. Reach the broken-off bridge where the sniper will be shooting from and stay there. Within a minute, all of the Grunts will have made their way under you, and they won't be able to shoot you from many angles (Literaly fish in a barrel). Check the edges and simply lob a grenade over the blind spot, and it should net you a grenade-related achievement/challenge.

Health: Very important to get all of the Health Upgrades (Light/Medium/Biotic Armor) as soon as possible. For both Light and Biotic Armor, you will have to melee a total of 30 Grunts. The Nerevarine mentionned to steer clear as much as possible from them, as they will take you out in one hit if you don't have armor. To make things easier, try this:
1. Whenever you see a Grunt shooting at you, just shoot him once - that shot will interrupt him, allowing you to get closer.
2. Shoot him a second time if you are covering a bigger distance or if you want to avoid the risk of meleeing him and getting zapped in the process.
3. One punch should do it after the second step, and it will still count as a melee kill, no matter how many bullet holes the Grunt has. :)
If you can obtain the Health Upgrades within the first few chapters, then the rest of the game will be much less difficult.

Hope this helps! Please leave a comment should you need more explanationa or if you voted down, and I'll answer the best I can.