Bionic Commando Rearmed 2

Story related, cannot miss.

The "Huge" thing the description is talking about is the giant Gorilla you have to face before crossing to the other island.

If you are going for a "No jump" and "Hard" run then let me tell you that it's impossible not to get hit while doing this. So I'd suggest using the Health Regeneration upgrade found in the first level. The boss itself isn't that hard. This is the basic strategy:

After the intro he'll raise his left hand (your right side) and turn it into electricity. Run to the opposite side and wait for the hand to return to its place, after that he'll mark the spots he's about to chop with his right hand (your left side). Just stay in the middle of the spots and he won't hit you.

After that he just repeats the above, but with the opposite side. When that is over, go to your right side and wait for his hand to raise, grab it and go up. He will turn his face to you, that's when you hit him, then grab his ear and pull, it will reveal a big red "eye" - shoot it until he closes his mouth.

Thanks to Barryms0083 for the video.