Blood Drive

The challenges in this game are pretty tough. The first two are pretty easy, just keep driving around firing your weapon.

first challenge, I used jackson, with tank loadout. from where you start, take the first big road on the left, it will have a harpoon, boost, and a wrench, grab the harpoon, drive to the end of the road, firing the whole time. when you reach the end u-turn and go back the way you came, like before just keep firing, keep doing this over and over. Watch your health. You should have no trouble keeping your spree up, remember it won't actually credit your spree until time runs out, then you'll get a time bonus.

The tough ones are the demolition ones. For the first demolition you must survive for a total of 5 minutes, I did it using nazar with the tank loadout and staying near the starting area. There is a wrench in front of you, there is also a rail gun in the area, and super wrench next to wrecked plane. Just keep making a loop getting each item when it appears, and you should be able to beat it. (NOTE: the time that is left on your counter when you die will be added to your total time)

EDIT: Thanks to the comments for pointing out that the demolition challenges are easier with Natalya.

As for the checkpoint challenge, I picked kelley with the ramming speed loadout, once you learn the checkpoints you shouldn't have much trouble.

The last challenge i used Natalya with the ramming speed loadout, basically just drive in a square and keep firing the drunk missiles, but keep and eye on your health.

I hope this helps as I don't see any guides for this game anywhere.