Castlevania: Lords of Shadow

Buying all combos will take roughly 105k experience. Two of them take 50k combined (Ultimate Light and Ultimate Shadow), so if those are done last you can pick up every other move in the game during the first playthrough.

Certain combos do not appear for purchase until other combos or purchased or certain relics are obtained. The last relic is obtained in Chapter VIII, after which all combos can be purchased assuming you have enough experience.

I posted a solution in the Veteran achievement of what I found to be the easiest way to get experience quickly. If you don't want to grind it out, one playthrough of the game is roughly 70k experience assuming all puzzles are solved without hints.