Mafia III: Definitive Edition

As the description says, you need to sell a single batch of weed for $10,000 or more. At first, $10,000 might seem like a lot of money but the final strain you unlock will guarantee you make a minimum of $10,000 for every batch sold.

The trick is to constantly use the Lab feature (unlocked at level 2) to add Hybrid seeds to your strains to make them better. At first, you will only have a few choices to make (as other seeds are locked until later levels) but the goal is to Hybridize a plant with any seed to increase its stats. Once you’ve planted that Hybrid plant, as soon as it's ready to be harvested you can Hybridize that same plant again to add even better stats to it!

It's hard to explain on paper but once you get the hang of it in-game, it makes sense! Here's what I used as an example to help you understand:

1. I recommend using the second strain, Ruderalis, which is unlocked when you reach level 2.
2. Before planting anything, go to the Lab section and choose to Hybridize the basic strain of Ruderalis.
3. I combined it with the second seed, Viride (increases Growth Rate so I wouldn't have to wait too long to plant more), to make a new strain (Let's call it "Rude1").
4. Plant Rude1 and wait until it's ready to harvest (which might take approx 1 hour).
5. Harvest Rude1 and sell it to whatever area gives you the most money (ignore the positive/negative %s, just look at the total profit at the top).
6. Now go back to the Lab, and choose to Hybridize Custom Strains (press on screen). Choose Rude1 instead of the original strain.
7. Add another seed to Rude1 (I did Viride again to make it grow really fast), now the new strain we will call "Rude2".
8. Plant Rude2 and wait until you can harvest it, then sell to the highest area.
9. Repeat the previous steps with Rude2 to create a new strain "Rude3" and repeat until you sell a batch for over $10,000.

To sum it up, you should be constantly using a newer version of that original strain each time to keep adding new stats to it until the stats are maxed out. Once the stats are maxed, you should have no trouble selling a batch for over $10,000.

Also the fourth strain Sativa will also get you over $10,000 the first time you plant it but it takes forever to grow. By the time you have it unlocked, you will have your Ruderalis strain almost maxed out though so it's much faster to keep using that.

One final note is fertilizer. It's incredibly useful to speed up the growth of your plants! With the first upgrade, you can harvest the plant when it reaches 80% completion instead of waiting until 100% but with the second upgrade you only need to wait until the plant hits 50% before you cab to harvest it. If you have a plant that has the best growth time (which is 18 in-game hours/36 real minutes) and you have the final Fertilizer upgrade, you can harvest it in 18 real minutes!