MLB 10: The Show

This is easier than it would appear. If you have gotten the Timing is Everything trophy, you now have a trophy award you can turn on from the main menu called Slow Run. Combine this with slider adjustments that include slower Baserunning and faster Fielder Speed. Now, just walk 2 runners and any ground ball to the left side of the infield should yield a triple play. If it's hit to third, tag the runner and throw to second. If it's to the shortstop, throw to third first. You should get the triple play in plenty of time. With this setup, a quadruple play would be easy if it were possible. If you have to, you can also edit the opposing team's Run Speed to zero.