Oddworld: Stranger's Wrath HD

Story-related. Cannot be missed.
The first boss in the game is an easy one and will show himself after you have cleared the wagon train crash site of all other Outlaws. Floyd will have two Outlaws with him, who can be lured away by using Chippunks and then dealt with accordingly. Make sure you have a Bolamite equipped on your crossbow, head up to Floyd (keep an eye on your radar and take cover when necessary) and shoot him with the Bolamite. His stamina will be very low so a single shot will wrap him up nicely for you to bounty alive.