Resistance 3

The HE .44 Magnum is available to you right from the start. Its primary fire shoots explosive rounds in to enemies, or the environment, which can then be detonated by pressing . Simply kill 5 Hybrids with one detonation (the detonation can be of multiple rounds, its doesn't just need to be a single shot), and the trophy will unlock. Keep in mind that the trophy specifies that it must by Hybrids. Grims, Leapers, or any other form of Chimera will not count.

Getting this trophy properly set up, finding 5 Hybrids close enough to each other, can be a bit difficult, as Hybrids like to move around. The best place I have found to get this trophy is through the checkpoint St. Louis, MO: Sewers. After entering the post office, a Brawler will arrive, as well as a large amount of hybrids on the second floor. Kill the Brawler, but be sure not to kill any of the hybrids that a shooting at you. The longer you stall the Brawler before killing it, the more Hybrids will show up. Once the brawlers is dead, all of the Chimera from the second floor will rush down the stairs towards you. There will be about 10 of them all running straight for you. This is the perfect place to kill 5 of them with one blast. Shoot a few magnum rounds into the floor or the group, then once you have 5 or 6 rounds lodged in to the area surrounding the Hybrids, press to detonate them. This will almost always kill 5 or more. If not, allow them to kill you and try again. It is best to do this on easy, so the Hyrbids don't kill you while you take out the Brawler, and so that the Hybrids go down easier.

Another good place to do this is at the checkpoint: New York, NY: Times Square. I'd recommend doing this on Casual difficulty. Here will be a large battle between several Hybrids and a Widowmaker. In the northwest corner of this are, all of the Hybrids will amass in one group and will all be shooting the Widowmaker. Follow the left wall and sneak up behind them. Wait a moment until there are 6 or 7 Hybrids in the group. They will be occupied with killing the Widowmaker, so you can carefully place your 6 explosive rounds before detonating them. Preferably, one round in each Hybrid. Once you have your full clip shot into, or near, the Hyrbids, press to detonate the rounds, killing all of the Hybrids. Note: Do not try doing this while going for "In This Together", as killing these Hybrids will negate that trophy.

Another good place to get this trophy is right at the end of the game. You will reach a point where you will be dangling from a rope and you will have the Magnum with infinite ammo. Simply shoot 6 bullets in to the crowds of Hybrids, then use to detonate.

If you are still finding this trophy troublesome, try coming back to these areas later after your Magnum is fully upgraded, because it will do more damage.