Ashina: The Red Witch

Story related and unmissable. This is your first major quest you beginning the game, and will have you fetching a lot of things for people.

• Go to the house in the lower right hand corner of the map and talk to Kappo to get the Boombox.
• Go the house in the lower middle of the map and go upstairs. Talk to Chomin, who requests sushi
• Go to the sushi restaurant in the center of the map and talk to Tanto. This will let you talk to Kanu, where you need to select the dialogue option "Sushi, please" for the sushi
• Take the sushi back to Chomin and give it to him to get the speakers
• Go to the house in the lower left hand corner of the map and talk to Trix, who wants you to catch a thief stealing her honey buns
• Go to the house in upper right hand corner of the map and talk to Oakie, who will give you the honey bun back (you can choose to give it back to him for the "A kind heart." achievement, it won't affect the quest line)
• Return to Trix and tell her you caught the thief to obtain the cassette tape
• Go to the house in the center left hand side of the map, go into the basement, and examine the chest to get the batteries
• Go to the tattoo shop above the ramen stand in the center of the map and examine the medical box at the top of the screen to get the wine
• Finally, talk to Gus at the ramen stand in the center of the map and give him the Boombox. The achievement will unlock at the end of the dialogue