Crash Team Rumble

Everyone will have their own favored hero/villain to use for this, but I personally found Cortex the best one for this achievement. He has a ray gun which can not only damage enemies from a distance, but it also has the ability to turn enemies into an animal for a few seconds, making them completely vulnerable.

I personally went in with him and the Healing Fridge equipped so I could heal myself if I took damage. Just make sure to keep a small distance between you and your enemy and only go for one at a time so as not to get multi-teamed.

I was also able to get the 10 knockouts in a single game using the same character, just throwing that out there.

This is what worked for me, I only hope it can help some others out there too. Good luck gamers!