Damnation

Insane mode is tricky as you tend to get downed quite quickly. I am no expert at this game but two tips made it very easy.

First off, play split screen co-op. Just play normally with you main controller, and leave your second controller alone. However, when you get downed, pick up your second controller, push LB to go into spirit mode, find your buddy (in blue) and then push RB to revive. You can do this from miles away, so your second controller never has to move. This way you never have to restart a checkpoint. At some points you will get swarmed and getting downed constantly, but you can just keep reviving and getting a kill in and rinsing and repeating till you get there.

Second is if you enter "BlowOffSomeSteam" as a cheat code you get a gun that kills in one shot. It's amazing and makes the game so much easier. Good luck!!

Boomtown is a fairly straight forward mission with no major boss at the end. If you are playing through by yourself take your time, use cover and your special ability to find the enemies. Let the AI do a lot of the work - you may have to revive him / her a lot but they will eventually get the job done.