Devil May Cry 2 HD

You can also farm in mission 9 when you need to escape from a burning building, in a room with lava you jump onto the lava and start dodging until you get SHOW TIME! and after that we take paired machine guns (actually these are MP5Ks, but oh well) and shoot them.

To farm Red Orbs, go to mission 13 to Arius. You will kill him in 0.5-1 minutes, and you will receive 5,000 orbs (2,000 for rank B and 3,000 for the boss)