Dishonored 2

Dishonored 2

50 Achievements

1,000

40-50h

Xbox One
Xbox Series
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Counter-serum

Counter-serum

Chatted with Dr. Hypatia aboard the Dreadful Wale

15

17.39%

How to unlock the Counter-serum achievement in Dishonored 2 - Definitive Guide

This is missable as it takes into account a choice you make at the end of the third mission.

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29 Aug 2020 07:52

During mission 3 you are are given the choice of curing or killing Hypatia. This achievement requires you to cure her. Follow the markers to create the serum then return and use it on her.

After the mission is over and you find yourself back on the Dreadful Wale, simply find Hypatia in a nearby cabin and talk to her to unlock the achievment.
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14 Nov 2016 00:00

You must use the non lethal solution to deal with the Crown Killer. She will be on the ship when you complete the mission.
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29 Oct 2019 01:14

This achievement is missable. It can only be earned if you eliminate Dr. Hypatia non-lethally during Mission 3, The Good Doctor.

The main objective in this mission is to track down and speak with Dr. Hypatia. Once you reach her location inside the Addemire Institute, ignore her completely. Instead, move towards the back of the room and speak with the patient (Hypatia's assistant) who is near death, laying down on a cot. He will inform you of the doctor's wrongdoings and of a method that can cure her insanity. This will initiate a secondary objective that asks you to create a counter-serum in the assistant's lab.

Follow the waypoint to your new objective, collect the necessary items to create the serum, and then interact with the flask on the assistant's work station. Grab the serum and return the morgue where you originally found Dr. Hypatia. Stealthily, you will need to approach the doctor from behind (or above) and hold to inject her with the serum. With this done, go on to finish the mission and once back aboard the Dreadful Wale, you can speak with Dr. Hypatia, thus unlocking the achievement.

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This achievement is missable. It can only be earned if you eliminate Dr. Hypatia non-lethally during Mission 3, The Good Doctor.

The main objective in this mission is to track down and speak with Dr. Hypatia. Once you reach her location inside the Addemire Institute, ignore her completely. Instead, move towards the back of the room and speak with the patient (Hypatia's assistant) who is near death, laying down on a cot. He will inform you of the doctor's wrongdoings and of a method that can cure her insanity. This will initiate a secondary objective that asks you to create a counter-serum in the assistant's lab.

Follow the waypoint to your new objective, collect the necessary items to create the serum, and then interact with the flask on the assistant's work station. Grab the serum and return the morgue where you originally found Dr. Hypatia. Stealthily, you will need to approach the doctor from behind (or above) and hold to inject her with the serum. With this done, go on to finish the mission and once back aboard the Dreadful Wale, you can speak with Dr. Hypatia, thus unlocking the achievement.

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Mission 3, "The Good Doctor". You must first rescue Dr. Hypatia, then talk to her after the rescue, after completing task 3, do not forget to visit Hypatia on board the fallen house.
Video tip from PowerPyx
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16 Nov 2016 11:32

Text guide to the achievement How to talk to Hypatia without killing
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19 Nov 2016 17:21