Disney Epic Mickey 2: The Power of Two

You will probably get this with no problem during a regular playthrough, but if you want to get it out of the way, quick and early, here is a nice solution:

When you get to Disney Gulch, drop down and head up the ramp to the left of the train (by the buildings), a machine will continue to spit out Spatters. Just continue to thin out the enemies with the help of Oswald and this cheevo will be yours in no time.

WARNING: If you befriend one of the Spatters, they will stop spawning.

Hope this helps everybody...

Thinderella (25G)
Destroy 100 enemies

I found that the best place to earn this is the Mad Doctor's Lab, while you are fighting against the Blotworx Dragon.

At the third stage of this fight you must move up an exposed path. On the top, three Blotling generators will continuously spawn Blotlings, and all you have to do is to kick them off the ledge, into the Thinner. One kick - one kill.
The Dragon will continue to attack, but it means no real danger.

You will have two achievements in a few minutes: "Junker (10G) - Destroy 50 enemies", and this one.

Got both the 50 & 100 in about 10 seconds (might be a glitch)

In the mad doctors attic first area, you have a large open space in which you have to shut down the replicators. Befriend all 3 of the first spatters (pirate, spider and apple head). Shut down the first replicator, now on my game all 3 spatters ran to the other replicator and starting smashing enemies as they spawned. Got achievements for 50 and then 100, 1 after the other in about 10 seconds.

I spent my entire playthrough only befriending so I would have had a really low count on the destroy side.