Fallout 4

EDIT: 04/24/23 I just received a message that the gazelles DO NOT count towards obtaining this achievement. Unfortunately I don't have the game anymore myself and can't check all the information mentioned in the comments in-game anymore. I deleted my original EDIT about gazelles being valid for this achievement based on the messages I received. Back in the day killing them worked for me, I just guess that they patched it. Happy hunting!



EDIT: 1/9/16 I just unlocked the achievement and I can confirm that it works with Newka-Cola and Nuka-Free. It isn't glitched either it is simply a huge pain in the butt. If you use any of the Nuka-mixes below you will have to face very short durations of the different effects on your character. You can push rb in the status screen of your pip boy to see if there is still an effect active. To give you an example: The Newka-Cola effect only lasted roughly 10 seconds. I could only kill around 2 enemies with one Newka-Cola. Feel free to use any of the mixes that you can create after picking up the various recipes in Nuka-World. Some of these will last much longer and will, therefore, make this achievement a lot more achievable . As mentioned in the comments, Nuka-Power seems to be the most effective mix because it has the longest duration of all the mixes.


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I want to point some things out, just to avoid confusion.

It is recommended that you do these kills before clearing all the different areas. It is easier to find enemies there than in the free areas around Nuka-World.
To get this achievement you need to kill creatures that are unique to Nuka-World. Similar to the "kill x Far Harbor enemies" achievement of the previous DLC, just killing mirelurks won't do to net you this achievements.

Another very important thing to keep in mind is the fact that you cannot just drink Nuka-Cola or any of its varieties like qunatum, dark, grape etc. You have to make sure to drink "Nuka-mixes". You can craft these via the new Nuka-mixer stations which are availiable in the crafting section in your settlements.
If you don't want to build stations on your own you can find some of them in Nuka-World as well. Refer to the comments section to get details about their location in Nuka-World.

There are 4 different stations, but all of them create the same mixes so it doesn't matter which one you build.

Also, it doesn't matter which mix you drink. All of them are valid for this achievement. From the get-go you can choose between the following 6 mixes:

Newka-Cola (Nuka-Cherry + Nuka-Cola)
Nuka-Buzz ( 2 Nuka-Cola Wild)
Nuka-Fancy ( Nuka-Cherry + Nuka-Cola Wild)
Nuka-Free ( Dirty Water + Nuka-Cola)
Nuka-Love ( Nuka-Cherry + Nuka-Cola Quartz)
Nuka-Twin (Nuka-Cola + Nuka-Cola Wild)

Additionally you can use all the mixes you get for the various recipes in Nuka-Word. If you have already completed the main missions, you can still kill enough enemies in the surroundings of Nuka-World.

You should not have any problems finding enough materials to mix those, since Nuka-World is crammed with all sorts of Nuka-Colas. Keep checking all the Nuka-Cola vending machines and you should always have enough in your inventory to mix the hell out of that stuff. If you, nevertheless, run out of Nuka-Cola try the Colonial Taphouse in Diamond City. They usually sell them there. If they are out of stock just wait for 48 hours.

The video below shows all the new creatures that are valid for this achievement:
(Video credit: WackyWeirdo)


EDIT: As BLAZE VII pointed out: "I think rats and ants are easy to farm. Also no need to go do Diamond City, Shelbie Chase in the NUKA-TOWN MARKET always sells a decent set. Just sit next to the red chair and wait 48h but again."

Hope this helps you guys!
Any improvements? Please let me know in the comments below!

Just to add to these other excellent solutions, I managed my 40 kills drinking only two mixes, note that I hadn't cleared the story missions so there were plenty of enemies to kill. What I used:

Nuka-Cooler (Quantum+Quartz+Victory), found out in the Galactic Zone, near the Star Control.
Nuka-Void (Dark+Quantum), found inside the Starlight Theatre, Galactic Zone. The recipe is right near the entrance, just watch out for the sentry.

I entered the Nuka Bottling Plant via the Quantum stream, ran all the way through grabbing the attention of as many Nukalurks as possible, drank the Cooler and killed everything. The Nukalurk Spawn enemies count! I then moved to the Bottling Plant exterior to find the Queens and Kings and more Spawns, was able to deal with most of these before the Cooler wore off.

After that, I went to Dry Rock Gulch, did most of the quests here before I remembered then drank the second mix (Void) as I entered Mad Mulligan's Mine. The achievement popped during the fight with the Queen at the end.

This seemed a lot more efficient than using Newka-Cola every 10 seconds or assaulting the Power Plant for the Nuka-Power recipe, but does need those story areas to get the number of enemies needed.

Press ~ to open Console.

tgm
player.additem 0021a53e 1
player.additem 000e6b2e 999999999
player.additem 06030eff 999999999
player.placeatme 0600ce60 55

Equip Big Boy and drink Newka-Cola.

Kill as many enemies as you can within 30 seconds. Repeat if necessary.

Made a quick video guide on how to get the achievement. I hope it helps all of you still having trouble.

I found the best Nuka mix to drink for this achievement is Nuka Void. It only takes 1 Nuka Quantum and 1 Nuka Dark to make & the effects last a few minutes

For those who like myself had finished the missions for the DLC then I suggest you follow this video guide as I did. It shows locations for regular spawns of enemy NPCs within Nuka World. With this I was able to get the achievement. All credit goes to the uploader of the video: MrReign

**DO THIS AS EARLY AS POSSIBLE WHEN PLAYING THE DLC**

1. Go to Cappy Cafe in Nuka-Town USA to get the Nuka-Cide recipe.

2. Go to Nuka-Town Market and talk to Shelbie Chase. She will sell you different flavors you’ll need to craft Nuka-Cide.

3. Go to Dry Rock Gulch, drink your Nuka-Cide, and start killing.

I chose Nuka-Cide for its early accessibility; you can get it before having to clear out sections of the park. It lasts 8 minutes, so you’ll have plenty of time to get kills before the effects wear off. Just be sure the pill icon in the bottom right corner of the screen is there before killing, I don’t remember seeing a notification when the effects wore off.

I was able to get this with only 2 Nuka-Cides. Hope this helps!

For me this only unlocked when I went to an old save and did all the kills without using VATS.

This is a tag-on for the other guides. I don't care about that one dude over there that said he got the achievement while infected with molerat disease. He's either lucky or a dog-faced pony soldier and I'll dip him in a vat of mayo and close the lid if he wants to catch these hands!

The quest in Vault 81 has you look for a cure to molerat disease for some kid, and if you so much as breathe too hard in that quest you'll get infected too. The end of the quest presents a moral dilemma where you heal the kid or heal yourself with the only cure.

If you didn't use it on yourself, you will permanently have molerat disease which lowers your hp by 10. It's not a big deal, except for the fact that I am 97% SURE that this permanent debuff is somehow interfering with this achievement's ability to track if you drank Nuka before a kill.

I have reloaded my save to before I started the DLC, random points within the DLC, and also during my main save, I can comfortably say that I've slain over 200 of these creatures IMMEDIATELY after downing a crafted nuka. I have every other achievement in the game. Since I don't have a save prior to contracting molerat disease, I now have no choice but to make a fresh save, grind to level 30 (which is the minimum to enter Nuka-World), and enter the DLC again!

I will let you guys know if the achievement pops properly after a totally unnecessary and unfair time-sink.

TL;DR THIS CHEEVO IS CLOSE TO, or IMPOSSIBLE TO GET IF YOU HAVE MOLERAT DISEASE!