Skeletal Avenger

As you progress through the game, you'll start to have quest options that force you through up to 6 levels to complete. The little icons with the blue dots on them indicate a perk to be obtained on that level. Some quests have paths that have multiple ×2 or even ×3 perk options. Choose one of these quests once they are available and make sure to collect all available perks (blue glowing orbs over dead bodies on the map). Some time you can even equip certain perks or clothing items that auto-reward you an additional perk at the beginning of a quest or floor. This makes it even easier. Once you reach 10 perks in a quest (usually right before fighting the boss of the final floor), the achievement should pop.