Spelunky 2

This trophy requires you to make it to the final boss and defeat them. Below is a short guide on how to approach the bossfight.
 
This trophy requires you to beat Tiamat, the first final boss of the game. She is located at the end of Neo-Babylon, the 6th area of the game. She will sit on her throne in the middle of the stage and spawn many different types of enemies, some more dangerous than others. Defeating her without the right equipment is tough so I would recommend you to try to bring at least one of the following items, if you plan on fighting her.
 
Shotgun: Probably the easiest and most practical way of killing her. The only place where she can be hurt is her head so try to get a good line of sight and start blasting her. She is surrounded by a small wall of blocks on both sides so you can either bomb these blocks and shoot at her from a distance or climb on top of blocks, drop a rope towards her and shoot her from this rope. Note that if you do not have a shotgun, you can get one by killing one of Madame Tusk's bodyguards, which can be found guarding the exits to her palace on 6-3. Just be careful that the bodyguard does not shoot you in the process. 
 
Freeze ray: If you manage to bring the Freeze Ray to this fight, you should be able to kill her in a matter of seconds by shooting her head, which will freeze her. Now jump on her head like you would a regular enemy. This kills her instantly.
 
Bombs: If you don't have any fancy weapons, you're going to have to make do with using your bombs. Using this method is much more difficult than the previous two,but it is still doable. You need to drop a bomb on the ground and pick it up again, "cooking" it, then throw it towards her face right before it explodes. She has a lot of health so you might need to throw multiple bombs to actually kill her. You might be inclined to use paste for this fight but sticking a bomb to her head causes her to roar, which flings the bomb right back at you. This does not mean that having paste makes this strategy unviable, just make sure you cook the bombs in the same way as you would without paste. 
 
Teleporter/Telepack/Axolotl: This is, in my opinion, the least practical strategy to face Tiamat but if you manage to bring either of these three items to the fight, just teleport on her face and it will kill her instantly. The axolotl requires you to do a double jump and press  a third time to teleport. The hard part of this strategy is getting this far with the item itself, seeing how easy it is to kill yourself with a misplaced teleport.