The Rabbit Hole

After the flipping painting disappears and you've collected all of the cards, open the closet door with the handle. There is a safe with 4 colored buttons on the front. The order in which you need to press them corresponds with the colors on the playing cards in order of the Royal Flush hand.

Press the following colors in order: Green, Blue, Orange, Red, Green
If you're having trouble distinguishing the colors: Right, Down, Left, Up, Right